Several members of the management team are the original founders of Isis Pharmaceuticals, Inc. Together, the executive committee has nearly a century of experience in advancing RNA-based technologies. The committee's collective industry experience, vision and dedication to RNA-based drug discovery and development, combined with your support, have made Isis a leader.

Stanley T. Crooke, M.D., Ph.D.
Chairman of the Board & Chief Executive Officer

B. Lynne Parshall, J.D.
Director, Chief Operating Officer & Chief Financial Officer

C. Frank Bennett, Ph.D.
Senior Vice President, Research

David J. Ecker, Ph.D.
Vice President of Isis & Chief Scientific Officer of Ibis Biosciences, Inc., a majority-owned subsidiary of Isis

Michael J. Treble
Vice President of Isis & President of Ibis Biosciences, Inc., a majority-owned subsidiary of Isis